Buffalo Bills vs Pittsburgh Steelers
Pittsburgh has never had a losing record in its 17 seasons with veteran Ben Roethlisberger at quarterback. The Steelers won their first 11 games last year, but they were unable to maintain that success.
The Bills burst onto the scene in 2020, appearing in the AFC title game where it lost to Kansas City. They won their final six regular season games en route to a 13-3 record.
The Steelers were bad to close out the 2020 season and they have to open the year in a very tough spot. Buffalo is going to have a packed house on hand for this game. The Bills went on a tear to close out last season and Allen could have an even bigger year in 2021.
Buffalo -6.5 @ 1.91
Over 48 @ 1.92